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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SFRS17A All Species: 6.36
Human Site: T452 Identified Species: 14
UniProt: Q02040 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02040 NP_005079.2 695 80735 T452 K K P D D S H T H D E L G V A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082042 696 80364 A452 K K P D D A H A H D E L G V A
Dog Lupus familis XP_548832 826 94556 T579 K K A D D P H T Q D E L G V S
Cat Felis silvestris
Mouse Mus musculus A2A3V1 959 111048 N402 C L G S T Q C N P Q E V G V M
Rat Rattus norvegicus Q9JLS3 1235 138732 R592 Q K R T Y K L R K E Q L K E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506426 409 47356 W182 L G G L P C K W F A R K E S G
Chicken Gallus gallus
Frog Xenopus laevis O42287 1270 143652 S747 L Y P F D A R S H D E I T I E
Zebra Danio Brachydanio rerio Q6PCR7 1267 151273 Q596 R E K E E L E Q R E A E L Q K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393797 721 84244 V354 R K K E E D K V S M K I A R E
Nematode Worm Caenorhab. elegans P46504 980 115327 E595 R S R L D A M E R E R E M L R
Sea Urchin Strong. purpuratus XP_781191 912 106093 E454 K E E K V Q E E K R E K L R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 95.4 75 N.A. 30.1 20.3 N.A. 50.2 N.A. 20.1 21.8 N.A. N.A. 32.3 20 33.1
Protein Similarity: 100 N.A. 97.1 78.4 N.A. 47.5 33.2 N.A. 52.6 N.A. 33.2 35.2 N.A. N.A. 50.9 35.7 49.8
P-Site Identity: 100 N.A. 86.6 73.3 N.A. 20 13.3 N.A. 0 N.A. 33.3 0 N.A. N.A. 6.6 6.6 13.3
P-Site Similarity: 100 N.A. 93.3 80 N.A. 26.6 33.3 N.A. 0 N.A. 60 33.3 N.A. N.A. 40 33.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 28 0 10 0 10 10 0 10 0 19 % A
% Cys: 10 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 28 46 10 0 0 0 37 0 0 0 0 0 % D
% Glu: 0 19 10 19 19 0 19 19 0 28 55 19 10 10 28 % E
% Phe: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % F
% Gly: 0 10 19 0 0 0 0 0 0 0 0 0 37 0 10 % G
% His: 0 0 0 0 0 0 28 0 28 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 19 0 10 0 % I
% Lys: 37 46 19 10 0 10 19 0 19 0 10 19 10 0 19 % K
% Leu: 19 10 0 19 0 10 10 0 0 0 0 37 19 10 0 % L
% Met: 0 0 0 0 0 0 10 0 0 10 0 0 10 0 10 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 28 0 10 10 0 0 10 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 19 0 10 10 10 10 0 0 10 0 % Q
% Arg: 28 0 19 0 0 0 10 10 19 10 19 0 0 19 10 % R
% Ser: 0 10 0 10 0 10 0 10 10 0 0 0 0 10 10 % S
% Thr: 0 0 0 10 10 0 0 19 0 0 0 0 10 0 0 % T
% Val: 0 0 0 0 10 0 0 10 0 0 0 10 0 37 0 % V
% Trp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % W
% Tyr: 0 10 0 0 10 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _